Which of the following statements about F-Gas regulations is true?

F-Gas regulations are designed to establish mandatory standards for the use and management of fluorinated gases to minimize their impact on climate change and to ensure environmental protection. The correct statement emphasizes the necessity of these regulations, which require individuals and organizations handling F-gases to be trained and certified. This mandatory framework is aimed at preventing leakage and ensuring that these potent greenhouse gases are handled, stored, and disposed of safely and responsibly.

The other options inaccurately represent the nature of the regulations. For instance, the regulations are not optional and apply to all professionals involved in the handling of F-gases, not just trained individuals. They also apply to all organizations, regardless of their size, which makes the statement about their application being limited to large organizations incorrect. Additionally, the regulations specifically focus on fluorinated gases and do not extend to natural refrigerants, which are not covered by the same F-Gas regulations. Thus, the statement that the regulations are mandatory for safe handling is accurate given the broader context of environmental standards and practices.